Article

The highly conserved stem-loop II motif is important for the lifecycle of astroviruses but dispensable for SARS-CoV-2

2022-05-02

Abstract excerpt

The stem-loop II motif (s2m) is an RNA element present in viruses from divergent viral families, including astroviruses and coronaviruses, but its functional significance is unknown. We created deletions or substitutions of the s2m in astrovirus VA1 (VA1), classic human astrovirus 1 (HAstV1) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). For VA1, recombinant virus could not be rescued upon parti...

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Identifiers and source

Literature Corpus work: 0bc16f71-8262-5caa-a0db-64871df5fd53
DOI: 10.1101/2022.04.30.486882

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