Article
Analysis of the ORF2 of human astroviruses reveals lineage diversification, recombination and rearrangement and provides the basis for a novel sub-classification system.
Archives of virology - 1 Dec 2014
Martella Vito, Pinto Pierfrancesco, Tummolo Fabio, De Grazia Simona, Giammanco Giovanni M, Medici Maria C, Ganesh Balasubramanian, L'Homme Yvan, Farkas Tibor, Jakab Ferenc, Bányai Krisztián
Abstract excerpt
Canonical human astroviruses (HAstVs) are important enteric pathogens that can be classified genetically and antigenically into eight types. Sequence analysis of small diagnostic regions at either the 5' or 3' end of ORF2 (capsid precursor) is a good proxy for prediction of HAstV types and for distinction of intratypic genetic lineages (subtypes), although lineage diversification/classification has not been...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.