Article

Sex does not Influence Neuronal Autophagy throughout Aging in Mice

2025-01-20

Abstract excerpt

<h4>ABSTRACT</h4> Autophagy is critical for the homeostasis and function of neurons, as misregulation of autophagy has been implicated in age-related neurodegenerative diseases and neuron-specific knockdown of early autophagy genes results in early neurodegeneration in mice. We previously found that autophagosome formation decreases with age in murine neurons. Sex differences have been intensely studied in neurod...

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Literature Corpus work: 0baad147-6d92-58f0-ac20-a74f94b2930a
DOI: 10.1101/2025.01.16.633428

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