Article

Time flies faster in epilepsy

2026-02-03

Abstract excerpt

<title>Abstract</title> <p>People with epilepsy have reduced life expectancy and increased age-related comorbidities, raising the possibility that epilepsy is associated with accelerated biological aging. Yet, direct and quantitative evidence for biological age acceleration in epilepsy has been limited. Here, we applied a tissue-specific DNA methylation-based epigenetic clock to brain and blood samples from 307 i...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 0b9a05c9-acdd-5842-9919-5f4c71728925
DOI: 10.21203/rs.3.rs-7773096/v2

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Time flies faster in epilepsyDOI 10.21203/rs.3.rs-7773096/v2Read

Time flies faster in epilepsySemantic proximity Read

Hippocampal and cortical tissue-specific epigenetic clocks indicate an increased epigenetic age in a mouse model for Alzheimer’s diseaseSemantic proximity Read

Cell-type specific epigenetic clocks to quantify biological age at cell-type resolutionSemantic proximity Read

Insights into ageing rates comparison across tissues from recalibrating cerebellum DNA methylation clockSemantic proximity Read

Back to the future: Epigenetic clock plasticity towards healthy agingSemantic proximity Read

An accelerated human in-vitro aging model mimics in-vivo aging and facilitates dynamic testing of anti-aging compoundsSemantic proximity Read

Epigenetic clock acceleration is linked to age-at-onset of idiopathic and <i>LRRK2</i> Parkinson’s diseaseSemantic proximity Read

Epigenetic Clock Acceleration Is Linked to Age at Onset of Parkinson's Disease.Semantic proximity Read

Genetic variants near MLST8 and DHX57 affect the epigenetic age of the cerebellum.Semantic proximity Read

Accelerated aging in bipolar disorders: An exploratory study of six epigenetic clocksSemantic proximity Read

Epigenetic aging in brain tissue of the self-fertilizing vertebrate, <i>Kryptolebias marmoratus</i>Semantic proximity Read

The Epigenetics of Epilepsy and Its ProgressionSemantic proximity Read