Article

Horizontally transferred cell-free chromatin particles function as autonomous satellite genomes and vehicles for transposable elements within host cells

2023-11-21

Abstract excerpt

<h4>Background</h4> Horizontal gene transfer (HGT) plays an important evolutionary role in prokaryotes, but it is thought to be less frequent in mammals. We previously reported that cell-free chromatin particles (cfChPs) - chromosomal fragments released from the billions of dying cells that circulate in human blood - are horizontally transferred to healthy cells with biological effects. However, the underlying me...

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Literature Corpus work: 0b8ccf27-64a0-5352-b251-74d7c660ca73
DOI: 10.1101/2023.11.21.567988

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