Article

Induction of pluripotent oncogenic stem cells from mouse fibroblasts

2024-11-07

Abstract excerpt

<h4>Summary</h4> Natural biological agents that can transform normal somatic cells into cancer stem cells, have not been identified. We earlier reported that cell free chromatin particles (cfChPs) that circulate in blood of cancer patients can horizontally transfer themselves to healthy cells to induce dsDNA breaks and inflammation. Here we show that a single cell clone D5 developed from NIH3T3 mouse fibroblast c...

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Literature Corpus work: c670ee3a-e5d4-5bb0-af9d-c04baf715a1a
DOI: 10.1101/2024.11.06.622204

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