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Article

How life changes itself: the Read-Write (RW) genome.

Physics of life reviews - 1 Sept 2013

Shapiro James A

Abstract excerpt

The genome has traditionally been treated as a Read-Only Memory (ROM) subject to change by copying errors and accidents. In this review, I propose that we need to change that perspective and understand the genome as an intricately formatted Read-Write (RW) data storage system constantly subject to cellular modifications and inscriptions. Cells operate under changing conditions and are continually modifying...

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Identifiers

PMID: 23876611
DOI: 10.1016/j.plrev.2013.07.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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