Article

Structural studies on the monotopic membrane protein, rotenone-insensitive NADH:ubiquinone oxidoreductase from Saccharomyces cerevisiae

2010-01-01

Abstract excerpt

Saccharomyces cerevisiae possesses three mitochondrial NADH:ubiquinone oxidoreductases. The rotenone-insensitive internal NADH:ubiquinone oxidoreductase [Ndi1] is solely responsible for the reduction of ubiquinone by mitochondrial matrix-derived NADH during the process of oxidative phosphorylation. Its homologues from Plasmodium and Mycobacterium bear particular relevance to the treatment of malaria and tuberculos...

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Literature Corpus work: 0b758a29-aa8f-5e61-b4f1-e0d50168e056
DOI: 10.25560/5658

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