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A Stable Reporter Cell Line to Study Respiratory Syncytial Virus NS2-Mediated Inhibition of <i>IFNB</i> Promoter Activation

2026-02-25

Abstract excerpt

Human respiratory syncytial virus (RSV) is an enveloped, non-segmented, negative-sense RNA virus and a major cause of severe lower respiratory tract disease in infants, older adults, and immunocompromised individuals. A hallmark of RSV pathogenesis is early evasion of innate immunity mediated by the non-structural proteins NS1 and NS2. NS2 is a multifunctional interferon (IFN) antagonist that dampens both IFNβ ind...

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Literature Corpus work
0b43151a-c68b-5898-bfda-cf8b9ec56068
DOI
10.64898/2026.02.24.706909
Open publication

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A Stable Reporter Cell Line to Study Respiratory Syncytial Virus NS2-Mediated Inhibition of <i>IFNB</i> Promoter ActivationDOI 10.64898/2026.02.24.706909
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