Article

Perturbation of PI3K/Akt Signaling Affected Autophagy Modulation in Dystrophin-deficient Myoblasts

2020-11-30

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> The absence of dystrophin has gave a massive impact on myotube development in Muscular Dystrophy pathogenesis. One of the conserved signaling pathways involved in skeletal muscle differentiation is the PI3K/Akt/mTOR pathway that plays a vital role in autophagy regulation. To further understand and establish targeted therapy in dystrophin-deficient myoblasts, pro...

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Literature Corpus work: 0b3a91ee-1db5-58f5-8fc6-99daa3ded9b6
DOI: 10.21203/rs.3.rs-113469/v1

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