Article

Perturbation of PI3K/Akt Signaling affected Autophagy Modulation in Dystrophin-Deficient Myoblasts

2020-10-28

Abstract excerpt

<title>Abstract</title> <p>The absence of dystrophin has gave a massive impact on myotube development in Muscular Dystrophy pathogenesis. One of the conserved signaling pathways involved in skeletal muscle differentiation is the PI3K/Akt/mTOR pathway that plays a vital role in autophagy regulation. To further understand and establish targeted therapy in dystrophin-deficient myoblasts, protein expression profiling...

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Literature Corpus work: 8d172236-db4f-50cb-870b-dbd17c18eee7
DOI: 10.21203/rs.3.rs-41896/v2

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