Article

Identification of cancer drivers from tumor-only RNA-seq with RNA-VACAY

2022-05-11

Abstract excerpt

Detecting somatic mutations is a cornerstone of cancer genomics and clinical genotyping; however, there has been little systematic evaluation of the utility of RNA sequencing (RNA-seq) for somatic variant detection and driver mutation analysis. Variants found in RNA-Seq are also expressed, reducing the identification of passenger mutations and would not suffer from annotation bias observed in whole-exome sequencin...

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Literature Corpus work: 0aeb8ecf-2fe6-5ae6-8c28-098c670bad7c
DOI: 10.1101/2022.05.10.491431

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