Article

Novel Insight into the Aetiology of Autism Spectrum Disorder Gained by Integrating Expression Data with Genome-wide Association Statistics

2018-11-29

Abstract excerpt

<h4>Background</h4> A recent genome-wide association study (GWAS) of autism spectrum disorders (ASD) (N cases =18,381, N controls =27,969) has provided novel opportunities for investigating the aetiology of ASD. Here, we integrate the ASD GWAS summary statistics with summary-level gene expression data to infer differential gene expression in ASD, an approach called transcriptome-wide association study (TWAS)....

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Literature Corpus work: 0aca2ea5-2a2c-53af-a754-4f14fbc622e8
DOI: 10.1101/480624

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