Article

Assessment of the Utility of Gene Positioning Biomarkers in the Stratification of Prostate Cancers

2019-08-08

Abstract excerpt

In eukaryotic cells, the genome is spatially organized in a non-random fashion within the confines of the interphase nucleus, and most genes occupy preferred nuclear positions. For some genomic loci these positioning patterns are context specific, reflected in the distinct location of certain genes and chromosomes in different cell types and in disease. Disease-related differential spatial positioning of genes has...

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Literature Corpus work: 0ac1a05b-60b5-584a-8d58-bd0603f7a47a
DOI: 10.1101/728972

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