Article

Controlling for Background Genetic Effects Using Polygenic Scores Improves the Power of Genome-wide Association Studies

2021-09-17

Abstract excerpt

Ongoing increases in the size of human genotype and phenotype collections offer the promise of improved understanding of the genetics of complex diseases. In addition to the biological insights that can be gained from the nature of the variants that contribute to the genetic component of complex trait variability, these data bring forward the prospect of predicting complex traits and the risk of complex genetic di...

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Literature Corpus work: 0aaf2371-366b-5705-9e89-d1efedec6fc2
DOI: 10.21203/rs.3.rs-873301/v1

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