Article

Whole genome duplication drove cell type evolution in the vertebrate brain

2025-07-04

Abstract excerpt

<title>Abstract</title> <p> The brains of vertebrates are more complex and have a wider diversity of cell types than those of their closest relatives. Whole-genome duplications (WGDs) occurred during early vertebrate evolution <sup>1</sup> , but it remains unclear whether the resultant duplicate genes (ohnologues) facilitated cell type evolution. Using brain single-cell transcriptomes from four vertebrates – h...

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Literature Corpus work: 0aa8eec2-0799-5b83-9d6a-31b7a4008646
DOI: 10.21203/rs.3.rs-6965966/v1

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