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Activation of the interleukin-3 gene by chromosome translocation in acute lymphocytic leukemia with eosinophilia [see comments]

1990-07-15

Abstract excerpt

The t(5;14)(q31;q32) translocation from B-lineage acute lymphocytic leukemia with eosinophilia has been cloned from two leukemia samples. In both cases, this translocation joined the IgH gene and the interleukin-3 (IL-3) gene. In one patient, excess IL-3 mRNA was produced by the leukemic cells. In the second patient, serum IL-3 levels were measured and shown to correlate with disease activity. There was no evidenc...

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Literature Corpus work
0a85a33e-fa49-5f78-ad86-80079eb36f66
DOI
10.1182/blood.v76.2.285.bloodjournal762285
Open publication

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Activation of the interleukin-3 gene by chromosome translocation in acute lymphocytic leukemia with eosinophilia [see comments]DOI 10.1182/blood.v76.2.285.bloodjournal762285
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