Article
The Genome in a Three-Dimensional Context: Deciphering the Contribution of Noncoding Mutations at Enhancers to Blood Cancer
2020-08-02
Abstract excerpt
Associations between blood cancer and genetic predisposition, including both inherited variants and acquired mutations and epimutations, have been well characterized. However, the majority of these variants affect noncoding regions, making their mechanisms difficult to hypothesize and hindering the translation of these insights into patient benefits. Fueled by unprecedented progress in next-generation sequencing a...
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Identifiers and source
- Literature Corpus work
- 0a7c279a-2dd5-5ee8-98f2-7e1e1506a11d
- DOI
- 10.20944/preprints202008.0007.v1