Article
Unraveling noncoding DNA variants and epimutations: a paradigm shift in hereditary cancer research.
Future oncology (London, England) - 1 Jan 2024
Ibrahim Maria Baz, Flanagan James, Ibrahim Tony, Rouleau Etienne
Abstract excerpt
Exhaustive efforts have been dedicated to uncovering genomic aberrations linked to cancer susceptibility. Noncoding sequence variants and epigenetic alterations significantly influence gene regulation and could contribute to cancer development. However, exploring noncoding regions in hereditary cancer susceptibility demands cutting-edge methodologies for functionally characterizing genomic discoveries....
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