Article
Quantitative Trait Loci Identify Functional Noncoding Variation in Cancer.
PLoS genetics - 1 Mar 2016
Heyn Holger
Abstract excerpt
The interpretation of noncoding alterations in cancer genomes presents an unresolved problem in cancer studies. While the impact of somatic variations in protein-coding regions is widely accepted, noncoding aberrations are mostly considered as passenger events. However, with the advance of genome-wide profiling strategies, alterations outside the coding context entered the focus, and multiple examples highlight...
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