Effects of fructose-exposed human mesangial cells on classical and alternative enzyme activities of Renin-Angiotensin System modulating peptides generation

Abstract excerpt

<title>Abstract</title> <p>Historically, proteolytic enzymes have been responsible for breaking peptide bonds between amino acids, catalyzing various reactions in metabolic pathways, and are important for maintaining and regulating these pathways. Recent studies have shown that the levels of various enzymes in the Renin-Angiotensin System (RAS), includingangiotensin-converting enzymes 1 and 2 (ACE and ACE2), neut...

Topics

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• Arteriosclerosis
• Hypertension, Renal
• Hypokalemia
• Polycystic Kidney Diseases
• Proteinuria
• Pseudohypoaldosteronism
• Receptors, Mineralocorticoid
• Syndrome

Identifiers and source

Literature Corpus work

0a613aaf-8d2c-551c-b4e5-4237b1ccff2d

DOI

10.21203/rs.3.rs-4432868/v1