Article
Mechanisms in nephrosclerosis and hypertension-beyond hemodynamics.
Journal of nephrology - 1 Jan 2000
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Abstract excerpt
These studies support that global glomerulosclerosis is a key lesion in human hypertensive nephrosclerosis, and cannot be simply explained by worse vascular sclerosis caused by higher blood pressure. Possible pathogenetic mechanisms include genetic susceptibility, accelerated aging and a primary microvascular disease. The potential importance of the renin angiotensin system in glomerular sclerosis is underscored...
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