Article

The impact of Indigenous American-like ancestry on risk of acute lymphoblastic leukemia in Hispanic/Latino children

2025-01-15

Abstract excerpt

Acute lymphoblastic leukemia (ALL) is the most common childhood cancer, with Hispanic/Latino children having a higher incidence of ALL than other racial/ethnic groups. Among genetic variants previously implicated in ALL risk, a number of them were found to be enriched in Indigenous American (IA)-like ancestries and inherited by many Hispanic/Latino individuals. However, due to potential confounding from environmen...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 0a5059e3-8c3c-5c52-bcd4-b99abf080d42
DOI: 10.1101/2025.01.14.25320563

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The impact of Indigenous American-like ancestry on risk of acute lymphoblastic leukemia in Hispanic/Latino childrenDOI 10.1101/2025.01.14.25320563Read

The impact of Indigenous American-like ancestry on the risk of acute lymphoblastic leukemia in Hispanic/Latino children.Semantic proximity Read

The emerging story of acute lymphoblastic leukemia among the Latin American population - biological and clinical implications.Semantic proximity Read

Ancestry and pharmacogenomics of relapse in acute lymphoblastic leukemia.Semantic proximity Read

Association of Genetic Ancestry With the Molecular Subtypes and Prognosis of Childhood Acute Lymphoblastic LeukemiaSemantic proximity Read

Genomic ancestry and somatic alterations correlate with age at diagnosis in Hispanic children with B-cell acute lymphoblastic leukemia.Semantic proximity Read

Toward Equitable Risk Classification for All Patients with T-ALL.Semantic proximity Read

Impact of Genetic Ancestry on T-cell Acute Lymphoblastic Leukemia OutcomesSemantic proximity Read

A noncoding regulatory variant in IKZF1 increases acute lymphoblastic leukemia risk in Hispanic/Latino children.Semantic proximity Read

Admixture mapping identifies a locus on 6q25 associated with breast cancer risk in US Latinas.Semantic proximity Read

Ancestry as a potential modifier of gene expression in breast tumors from Colombian women.Semantic proximity Read

Impact of Genetic Ancestry on Genomics and Survival Outcomes in T-cell Acute Lymphoblastic LeukemiaSemantic proximity Read

Amerindian genetic ancestry and INDEL polymorphisms associated with susceptibility of childhood B-cell Leukemia in an admixed population from the Brazilian AmazonSemantic proximity Read