Article

Mirror effect of genomic deletions and duplications on cognitive ability across the human cerebral cortex

2025-01-07

Abstract excerpt

Cognitive deficits are common across many neurodevelopmental and psychiatric conditions, including those studied in the current set of PGC-CNV papers. How changes in regional gene expression across the cerebral cortex influence cognitive ability remains unknown. Population variation in gene dosage -which significantly impacts gene expression-represents a unique paradigm to address this question. We developed a cer...

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Identifiers and source

Literature Corpus work: 09fe50cd-466d-504a-afa9-f73018bb31a8
DOI: 10.1101/2025.01.06.631492

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