Article

1q21.1 distal copy number variants are associated with cerebral and cognitive alterations in humans

2021-01-15

Abstract excerpt

<p>Low-frequency 1q21.1 distal deletion and duplication copy number variant (CNV) carriers are predisposed to multiple neurodevelopmental disorders including schizophrenia, autism and intellectual disability. Human carriers display a high prevalence of micro- and macrocephaly in deletion and duplication carriers, respectively. The underlying brain structural diversity remains largely unknown.We systematically call...

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Literature Corpus work: 1b4c9c55-7075-57f8-bc4c-af097b18907f
DOI: 10.31234/osf.io/tbjxh

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