Article

The kinetics and fragmentation of cell-free DNA from cultured cancer cells are influenced by anticancer treatments

2022-08-02

Abstract excerpt

Liquid biopsy-based detection of circulating free DNA (cfDNA) is a promising tool to monitor tumor progression and treatment response. cfDNA release is thought to result from a combination of cell death (apoptosis and necrosis), and active cellular secretion. As such, cytotoxic anti-cancer therapies can impact cfDNA kinetics. This makes the interpretation of cfDNA analyses pivotal for its applicability as a biomar...

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Literature Corpus work: 09bfd0db-79eb-58ab-85ad-b8a91a352d86
DOI: 10.21203/rs.3.rs-1891499/v1

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