Article

p53 Dry Gene Powder Enhances Anti-cancer Effects of Chemotherapy against Malignant Pleural Mesothelioma

2022-10-26

Abstract excerpt

Dry gene powder is a novel gene-delivery system, which is inhalable and not infectious with high gene expression. Previously, we showed that the transfection of p16 INK4a or TP53 by dry gene powder resulted in growth inhibitions of lung cancer and malignant pleural mesothelioma (MPM) in vitro and in vivo . Here, we report that dry gene powder containing p53- expression-plasmid DNA enhanced the therapeutic effects...

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Literature Corpus work: 09a271d8-3474-5e28-b0e7-8d9acd338aff
DOI: 10.21203/rs.3.rs-2137518/v1

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