Article

Hsp22 is the key sensor and balancer in mitochondrial dynamic associated metabolic reprogramming

2020-11-23

Abstract excerpt

Altered mitochondrial dynamics are commonly seen in tumors and Parkinson’s disease (PD), but the exact mechanism is unclear. We observed in tumor and PD flies, interference of mitochondrial fission or fusion reverses metabolic reprogramming and attenuates pathogenic phenotypes, indicating the rebalanced mitochondrial dynamics can re-establish cellular homeostasis. Surprisingly, we found Hsp22 is highly induced in...

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Identifiers and source

Literature Corpus work: 099ce941-a6a7-5c85-8ef8-a7de1534e41c
DOI: 10.1101/2020.11.22.393116

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