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Article

Strategy to Estimate Sample Sizes to Justify the Association between MMP1 SNP and Osteoarthritis.

Genes - 17 Jun 2022

Kao Chung-Cheng, Hsu Hsiang-En, Lai Jen-Chieh, Chen Hsiang-Cheng, Chuang Su-Wen, Lee Meng-Chang

Abstract excerpt

Background: the impact of knee osteoarthritis (OA) poses a formidable challenge to older adults. Studies have reported that genetic factors, such as MMP1, are one of important risk factors for knee OA. Although the relationship between the genetic polymorphism of MMP1 rs1799750 and the risk of knee OA has been explored, conclusions have been nonunanimous and pending due to research sample sizes, one of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35741844
DOI: 10.3390/genes13061084
PMCID: PMC9222496

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