Article
Association of MMP-1 -1607 1G/2G (rs1799750) polymorphism with primary knee osteoarthritis in the Greek population.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society - 1 Sept 2014
Lepetsos Panagiotis, Pampanos Andreas, Kanavakis Emmanouil, Tzetis Maria, Korres Dimitrios, Papavassiliou Athanasios G, Efstathopoulos Nicolaos
Abstract excerpt
Osteoarthritis is the most common form of arthritis with still unknown pathogenic etiology and considerable contribution of genetic factors. One of the mechanisms of cartilage degradation in osteoarthritis is enzymatic proteolysis of the extracellular matrix by metalloproteinases. MMP-1, produced...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
