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Article

Association between the MMP-1-1607 1G/2G Polymorphism and Osteoarthritis Risk: A Systematic Review and Meta-Analysis.

BioMed research international - 1 Jan 2020

Liu Jiankun, Wang Guangye, Peng Zhan

Abstract excerpt

BACKGROUND: Osteoarthritis (OA) is a common disease characterized by articular cartilage degeneration and secondary hyperosteogenesis. Genetic factors are associated with the occurrence of OA. While several studies have shown that the matrix metalloproteinase-1- (MMP-1-) 1607 1G/2G (rs1799750) polymorphism may be related to the occurrence and development of OA, there is inconsistency in the literature. To better...

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PMID: 32596320
DOI: 10.1155/2020/5190587
PMCID: PMC7273398

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