Article

Differential Gene Expression Analysis of Oocytes in a PCOS Mouse Model Revealed the Relation of Ribosomal Pathway

2022-01-07

Abstract excerpt

Polycystic ovary syndrome (PCOS), a common endocrinal disorder, is associated with impaired oocyte development, which leads to infertility. However, the pathogenesis of PCOS has not been completely elucidated. This study aimed to analyze the differentially expressed genes (DEGs) and epigenetic changes in the oocytes of the PCOS mouse model to identify the etiological factors. In this study, RNA-sequencing analysis...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 098358e6-29b3-58b3-8efd-da4e5e7dfdd2
DOI: 10.21203/rs.3.rs-1191412/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Differential Gene Expression Analysis of Oocytes in a PCOS Mouse Model Revealed the Relation of Ribosomal PathwayDOI 10.21203/rs.3.rs-1191412/v1Read

Upregulated Ribosomal Pathway Impairs Follicle Development in a Polycystic Ovary Syndrome Mouse Model: Findings of Differential Gene Expression Analysis of OocytesSemantic proximity Read

Dynamic changes in the transcriptome of oocytes during adolescent-onset PCOS in miceSemantic proximity Read

Loss of oocyte Rps26 in mice arrests oocyte growth and causes premature ovarian failureSemantic proximity Read

Bioinformatics analysis of the role of RNA modification regulators in polycystic ovary syndromeSemantic proximity Read

Identification of lncRNA expression profiles associated with ovarian development and ageing process in miceSemantic proximity Read

Transcriptome-wide association study identified candidate genes associated with polycystic ovary syndromeSemantic proximity Read

RNA-Seq transcriptome reveals different molecular responses during human and mouse oocyte maturation and fertilizationSemantic proximity Read

Maternal factor PABPN1L is essential for maternal mRNA degradation during maternal-to-zygotic transitionSemantic proximity Read

Proteome of mouse oocytes at different developmental stagesSemantic proximity Read

The Identification And Functional Analysis Of Circrnas In Endometrial Receptivity Of Mice With Polycystic Ovary SyndromeSemantic proximity Read

Increased Environment-Related Metabolism and Genetic Expression in the In Vitro Matured Mouse Oocytes by Transcriptome AnalysisSemantic proximity Read

The transcriptome of human oocytesSemantic proximity Read