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Proteome of mouse oocytes at different developmental stages

27 Sept 2010

Abstract excerpt

The mammalian oocyte possesses powerful reprogramming factors, which can reprogram terminally differentiated germ cells (sperm) or somatic cells within a few cell cycles. Although it has been suggested that use of oocyte-derived transcripts may enhance the generation of induced pluripotent stem cells, the reprogramming factors in oocytes are undetermined, and even the identified proteins composition of oocytes is...

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PMID: 20876089
DOI: 10.1073/pnas.1013185107

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