Article

Critical nodes reveal peculiar features of human essential genes and protein interactome

2019-11-05

Abstract excerpt

Network-based ranking methods (e.g., centrality analysis) have found extensive use in systems biology and network medicine for the prediction of essential proteins, for the prioritization of drug targets candidates in the treatment of several pathologies and in biomarker discovery, and for human disease genes identification. We here studied the connectivity of the human protein-protein interaction network ( i.e....

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Literature Corpus work: 0966f30f-422a-54a2-b0fc-5cd3e7657ce7
DOI: 10.1101/831750

Open publication

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