Article

Propionic acid induces dendritic spine loss by MAPK/ERK signaling and dysregulation of autophagic flux

2020-05-22

Abstract excerpt

<title>Abstract</title> <p>Propionic acid (PPA) is a short-chain fatty acid that is an important mediator of cellular metabolism. It is also a by-product of human gut enterobacteria and a common food preservative. A recent study found that rats administered with PPA showed autistic-like behaviors like restricted interest, impaired social behavior, and impaired reversal in a T-maze task. This study aimed to identi...

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Literature Corpus work: 09666285-a8ef-50c3-9451-cc17c4e095dd
DOI: 10.21203/rs.3.rs-15401/v2

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