Article

Subcellular localization of fibroblast growth factor receptor type 2 and correlation with CTNNB1 genotype in adrenocortical carcinoma

2020-06-01

Abstract excerpt

<title>Abstract</title> <p>Objective: Fibroblast growth factor receptor (FGFR)2 regulates the development of the adrenal gland in mice. In addition, FGFR2-mediated signalling has been shown to prevent apoptosis and to enhance proliferation in adrenocortical precursor cells. The activation of the Wingless/Int-1 (WNT) / beta catenin pathway as a key mechanism of adrenocortical tumourigenesis has been linked to FGFR...

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Literature Corpus work: 08c9fad4-b1df-59e0-80e2-cf38aac66156
DOI: 10.21203/rs.2.24557/v3

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