Article

DENTIST – using long reads for closing assembly gaps at high accuracy

2021-02-27

Abstract excerpt

<h4>Background</h4> Long sequencing reads allow increasing contiguity and completeness of fragmented, short-read based genome assemblies by closing assembly gaps, ideally at high accuracy. While several gap closing methods have been developed, these methods often close an assembly gap with sequence that does not accurately represent the true sequence. <h4>Findings</h4> Here, we present DENTIST, a sensitive, high...

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Literature Corpus work: 08adc9fd-f8be-5bc7-84e8-04d889363b69
DOI: 10.1101/2021.02.26.432990

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