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Article

LOCAS--a low coverage assembly tool for resequencing projects.

PloS one - 1 Jan 2011

Klein Juliane D, Ossowski Stephan, Schneeberger Korbinian, Weigel Detlef, Huson Daniel H

Abstract excerpt

MOTIVATION: Next Generation Sequencing (NGS) is a frequently applied approach to detect sequence variations between highly related genomes. Recent large-scale re-sequencing studies as the Human 1000 Genomes Project utilize NGS data of low coverage to afford sequencing of hundreds of individuals. Here, SNPs and micro-indels can be detected by applying an alignment-consensus approach. However, computational methods...

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PMID: 21858125
DOI: 10.1371/journal.pone.0023455
PMCID: PMC3156226

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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