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Whole-mouse <i>in vivo</i> bioluminescence imaging applied to drug screening against <i>Leishmania infantum</i> : a reliable method to evaluate efficacy and optimize treatment regimens

2018-05-18

Abstract excerpt

<h4>ABSTRACT</h4> Leishmaniasis is an important vector-borne neglected tropical disease caused by Leishmania parasites. Current anti- Leishmania chemotherapy is unsatisfactory, justifying the continued search for alternative treatment options. Herein, we propose the use of a minimally invasive bioluminescence-based murine model for preliminary in vivo screening of compounds against visceral infection by Leish...

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Literature Corpus work
0881911b-6591-5c15-98c5-3be3d6606be2
DOI
10.1101/326355
Open publication

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Whole-mouse <i>in vivo</i> bioluminescence imaging applied to drug screening against <i>Leishmania infantum</i> : a reliable method to evaluate efficacy and optimize treatment regimensDOI 10.1101/326355
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