Back to search

Article

Mutation of the peptide-regulated transcription factor ComR for amidated peptide specificity and heterologous function in <i>Lactiplantibacillus plantarum</i> WCFS1

2024-01-26

Abstract excerpt

There is a growing interest in the use of probiotic bacteria as biosensors for the detection of disease. However, there is a lack of bacterial receptors developed for specific disease biomarkers. Here, we have investigated the use of the peptide-regulated transcription factor ComR from S treptococcus spp . for specific peptide biomarker detection. ComR exhibits a number of attractive features that are potentially...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
0863f0d9-7570-55ec-8c48-cf86f423ebe7
DOI
10.1101/2024.01.25.577207
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Mutation of the peptide-regulated transcription factor ComR for amidated peptide specificity and heterologous function in <i>Lactiplantibacillus plantarum</i> WCFS1DOI 10.1101/2024.01.25.577207
Mutation of the peptide-regulated transcription factor ComR for amidated peptide specificity and heterologous function in Lactiplantibacillus plantarum WCFS1.Semantic proximity
Synthetic gene circuits enable systems-level biosensor discovery at the host-microbe interfaceSemantic proximity
Engineered probiotic <i>Lactobacillus plantarum</i> WCSF I for monitoring and treatment of <i>Staphylococcus aureus</i> infectionSemantic proximity
A discovery platform to identify inducible synthetic circuitry from varied microbial sourcesSemantic proximity
Mining Microbial Transcriptomes to Engineer Cell-Based Bacterial Biosensors in Gut-Resident BacteroidaceaeSemantic proximity
Competence Inhibition by the XrpA Peptide Encoded Within the <i>comX</i> Gene of <i>Streptococcus mutans</i>Semantic proximity
Implementation of Probiotic Bacteria for Monitoring Intestinal InflammationSemantic proximity
Structure–Activity Relationships of the Competence Stimulating Peptide in Streptococcus mutans Reveal Motifs Critical for Membrane Protease SepM Recognition and ComD Receptor ActivationSemantic proximity
Pheromone Recognition and Selectivity by ComR Proteins among Streptococcus SpeciesSemantic proximity
Expanding the <i>Bacteroides</i> synthetic biology toolkit to develop an <i>in vivo</i> intestinal malabsorption biosensorSemantic proximity
Discovery of novel peptides regulating competence development in Streptococcus mutans.Semantic proximity
Dynamic evolution of bacterial ligand recognition by formyl peptide receptorsSemantic proximity
Select a neighboring publication to make it the new centre.