Article

Interleukin-37 suppresses oxidized-LDL induced pro-osteogenic response by downregulating NF-κB and PERK-eIF2alpha-ATF4 pathways in human coronary artery endothelial cells

2024-01-30

Abstract excerpt

OBJECTIVE: Coronary atherosclerosis is an age-related disease that originates from osteogenic differentiation of coronary arterial endothelial cells (CAECs) induced by intimal injury. CAECs express excess levels of osteogenic factors in response to oxidative stress. This study aims to investigate the effect of IL-37 on high cellular level of oxidized low-density lipoprotein (ox-LDL) -induced CAECs and its potentia...

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Literature Corpus work: 085e159f-e378-5431-9aca-9a7998abfb98
DOI: 10.22541/au.170663741.19877184/v1

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Interleukin-37 suppresses oxidized-LDL induced pro-osteogenic response by downregulating NF-κB and PERK-eIF2alpha-ATF4 pathways in human coronary artery endothelial cellsDOI 10.22541/au.170663741.19877184/v1Read

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