Article

Panel Informativity Optimizer (PIO): an R package to improve cancer NGS panel informativity

2021-06-24

Abstract excerpt

<h4>ABSTRACT</h4> Mutation detection by next generation sequencing (NGS) is routinely used for cancer diagnosis. Selecting an optimal set of genes for a given cancer is not trivial as it has to optimize informativity ( i.e . the number of patients with at least one mutation in the panel), while minimizing panel length in order to reduce sequencing costs and increase sensitivity. We propose herein Panel Informati...

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Literature Corpus work: 085be693-0fb4-5524-bc05-9e0bec8111db
DOI: 10.1101/2021.06.23.449561

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