Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Rational design of cancer gene panels with OncoPaD.

Genome medicine - 3 Oct 2016

Rubio-Perez Carlota, Deu-Pons Jordi, Tamborero David, Lopez-Bigas Nuria, Gonzalez-Perez Abel

Abstract excerpt

BACKGROUND: Profiling the somatic mutations of genes which may inform about tumor evolution, prognostics and treatment is becoming a standard tool in clinical oncology. Commercially available cancer gene panels rely on manually gathered cancer-related genes, in a "one-size-fits-many" solution. The design of new panels requires laborious search of literature and cancer genomics resources, with their performance on...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Pharmacological
Share to Carcinogenesis
Share to Cost-Benefit Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Databases, Genetic

Share to Neoplasm Proteins

Share to Oncogenes

Share to Software

Share to Software Design

Source

Open in PubMed Open full text

Identifiers

PMID: 27716338
DOI: 10.1186/s13073-016-0349-1
PMCID: PMC5047348

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Rational design of cancer gene panels with OncoPaD.PMID 27716338Read ↗

Panel Informativity Optimizer: An R Package to Improve Cancer Next-Generation Sequencing Panel Informativity.Semantic proximity Read ↗

Broad versus limited gene panels to guide treatment in patients with advanced solid tumors: a randomized controlled trialSemantic proximity Read ↗

Systematic pan-cancer analysis of mutation-treatment interactions using large real-world clinicogenomics data.Semantic proximity Read ↗

Panel Informativity Optimizer (PIO): an R package to improve cancer NGS panel informativitySemantic proximity Read ↗

CAN-Scan: A multi-omic phenotype-driven precision oncology platform identifies prognostic biomarkers of therapy response for colorectal cancerSemantic proximity Read ↗

Multi-omics alleviates the limitations of panel-sequencing for cancer drug response predictionSemantic proximity Read ↗

Panel Sequencing for Targeted Therapy Selection in Solid Tumors.Semantic proximity Read ↗

OncoRisk: a state-of-the-art web server for bridging the oncogenic databases and pan-cancer cohorts to the translational oncology.Semantic proximity Read ↗

Clinical and Technical Validation of OncoIndx® Assay – A Comprehensive Genome Profiling Assay for Pan-Cancer InvestigationsSemantic proximity Read ↗

Use of an Integrated Pan-Cancer Oncology Enrichment Next-Generation Sequencing Assay to Measure Tumour Mutational Burden and Detect Clinically Actionable Variants.Semantic proximity Read ↗

OncoRisk: A state-of-the-art Web Server for bridging the oncogenic databases and pan-cancer cohorts to the translational oncologySemantic proximity Read ↗

Development and validation of a multigene variant profiling assay to guide targeted and immuno therapy selection in solid tumors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.