Article

The Quality Sequencing Minimum (QSM): providing comprehensive, consistent, transparent next generation sequencing data quality assurance

2018-04-04

Abstract excerpt

Next generation sequencing (NGS) is routinely used in clinical genetic testing. Quality management of NGS testing is essential to ensure performance is consistently and rigorously evaluated. Three primary metrics are used in NGS quality evaluation: depth of coverage, base quality and mapping quality. To provide consistency and transparency in the utilisation of these metrics we present the Quality Sequencing Minim...

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Literature Corpus work: a6c1bb1f-79cd-5287-849a-98e56f41140b
DOI: 10.12688/wellcomeopenres.14307.1

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