Article

Systemic circulating microRNA landscape in Lynch syndrome

2022-03-12

Abstract excerpt

MicroRNAs (miRs) are non-coding RNA-molecules that regulate gene expression. Global circulating miR (c-miR) expression patterns (c-miRnome) change with carcinogenesis in various sporadic cancers. Therefore, aberrantly expressed c-miRs could have diagnostic, predictive and prognostic potential in molecular profiling of cancers. c-miR functions in carriers of inherited pathogenic mismatch-repair gene variants ( pat...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 084a5ba9-f8b6-53f7-822b-c38602108eca
DOI: 10.1101/2022.03.10.483718

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Systemic circulating microRNA landscape in Lynch syndromeDOI 10.1101/2022.03.10.483718Read

Multi-omics Approaches to Uncover Liquid-Based Cancer-Predicting Biomarkers in Lynch SyndromeSemantic proximity Read

Lynch Syndrome Biopathology and Treatment: The Potential Role of microRNAs in Clinical PracticeSemantic proximity Read

Estimating cancer risk in carriers of Lynch syndrome variants in UK BiobankSemantic proximity Read

Genomic and transcriptomic heterogeneity of colorectal tumours arising in Lynch syndrome.Semantic proximity Read

Germline miRNA DNA variants and the risk of colorectal cancer by subtype.Semantic proximity Read

Recent Advances in Lynch Syndrome: Diagnosis, Treatment, and Cancer PreventionSemantic proximity Read

Tracing the stemness and malignant transition in a heritable colorectal cancer Lynch Syndrome by single-cell RNA-seq analysisSemantic proximity Read

Lynch syndrome - cancer pathways, heterogeneity and immune escape.Semantic proximity Read

Distinct mutational profile of Lynch syndrome colorectal cancers diagnosed under regular colonoscopy surveillanceSemantic proximity Read

Deciphering of Somatic Mutational Signatures of CancerSemantic proximity Read

Colorectal Cancers with Microsatellite Instability Display Unique miRNA ProfilesSemantic proximity Read

Estimating cancer risk in carriers of Lynch syndrome variants in UK Biobank.Semantic proximity Read