Article

Selective effects of estradiol on human corneal endothelial cells

2023-04-28

Abstract excerpt

Fuchs endothelial corneal dystrophy (FECD) results from genetic and environmental factors triggering mitochondrial and oxidative stress in corneal endothelial cells (CEnCs) leading to CEnC death and corneal opacification. FECD is more common in women than men, but the basis for this observation is unknown. Because FECD is commonly diagnosed around the time of the menopausal transition in women when estrogen levels...

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Literature Corpus work: 08459da5-f6de-5225-a6e1-33bdbff9367b
DOI: 10.1101/2023.04.27.538629

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