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Mitochondrial Dysfunction and Mitophagy in Fuchs Endothelial Corneal Dystrophy

26 Jul 2021

Abstract excerpt

Fuchs endothelial corneal dystrophy (FECD) is a genetically complex, heterogenous, age-related degenerative disease of corneal endothelial cells (CEnCs), occurring in the fifth decade of life with a higher incidence in females. It is characterized by extracellular matrix (ECM) protein deposition called corneal guttae, causing light glare and visual complaints in patients. Corneal transplantation is the only...

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PMID: 34440658
DOI: 10.3390/cells10081888

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