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SARS-CoV-2 Omicron: Viral Evolution, Immune Evasion, and Alternative Durable Therapeutic Strategies.

Viruses - 28 Apr 2024

Guo Hailong, Ha Sha, Botten Jason W, Xu Kai, Zhang Ningyan, An Zhiqiang, Strohl William R, Shiver John W, Fu Tong-Ming

Abstract excerpt

Since the SARS-CoV-2 Omicron virus has gained dominance worldwide, its continual evolution with unpredictable mutations and patterns has revoked all authorized immunotherapeutics. Rapid viral evolution has also necessitated several rounds of vaccine updates in order to provide adequate immune protection. It remains imperative to understand how Omicron evolves into different subvariants and causes immune escape as...

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Identifiers

PMID: 38793580
DOI: 10.3390/v16050697
PMCID: PMC11125895

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