Article

CD9, a potential leukemia stem cell marker, regulates drug resistance and leukemia development in acute myeloid leukemia

2021-01-14

Abstract excerpt

<h4>Background: </h4> Leukemia stem cells (LSCs) are responsible for the initiation, progression and relapse of acute myeloid leukemia (AML). Therefore, a therapeutic strategy targeting LSCs is a potential approach to eradicate AML. In this study, we aimed to identify LSC-specific surface markers and uncover the underlying mechanism of AML LSCs. <h4>Methods: </h4>: Microarray gene expression data were used to inve...

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Literature Corpus work: 079b0b6b-fde5-5744-9163-7bf3126b15f8
DOI: 10.21203/rs.3.rs-55355/v3

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