Article

Generation of transplantable and biologically responsive colonic tissue from human induced pluripotent stem cells using a rapid co-differentiation platform

2023-12-09

Abstract excerpt

<h4>Background</h4> The colonic mucosa consists of cell populations derived from multiple lineages. Induced pluripotent stem cells (iPSCs) are capable of generating large numbers of differentiated cells from any lineage. Thus, iPSCs are highly versatile for derivation of intestinal cells for generation of colonic mucosal tissue for clinical and biological applications. <h4>Objective</h4> We set out to create a h...

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Literature Corpus work: 06f7c7e3-cec5-5d2d-be06-512696b7ac60
DOI: 10.1101/2023.12.08.570795

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